Disease
Disease
- hAPP tg Mice
Mice overexpressing human APP751SL with AD like brain pathology and behavioural deficits.
- hTAU tg Mice TAU441
Mice overexpressing human TAU441 empower an exploratíon of abnormally hyperphosphorylated TAU accumulations.
- AD11 Mice
Mouse model showing AD pathology due to NGF sequestration
- p75NTR Mice
For testing strategies to interfere with p75NTR mediated cell death
- β-Amyloid Injection
A model of Alzheimer's disease to investigate in vivo new compounds with neuroprotective potential.
- Scopolamine Treated Mice
The model system based on cholinergic antagonism
- α-Synuclein tg Mice
Mice overexpressing wt human α-synuclein - described as D-line (Masliah et al. 2000).
- MPTP Mouse Model
A tool to investigate drug actions on dopamine related neuronal cell death in PD.
- Behaviour Testing
A wide range of behavioural tests enables addressing questions concerning the cognitive and neural basis of learning and memory.
- Drosophila Based AD & HD Models
Screening platform for potential AD & HD compounds